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InnovAiT 2009 2(11):662-673; doi:10.1093/innovait/inp144
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© The Author 2009. Published by Oxford University Press on behalf of the RCGP. All rights reserved. For permissions please e-mail: journals.permissions@oxfordjournals.org

Pancreatic disease

Mr James A. Stephenson

Clinical Research Registrar, Department of Hepatobiliary and Pancreatic Surgery, University Teaching Hospitals of Leicester, Leicester General Hospital, Leicester

Mr Omer Al-Taan

Clinical Research Registrar

Mr Matthew S. Metcalfe

Consultant Hepatobiliary and Pancreatic Surgeon

Mr Ashley R. Dennison

Consultant Hepatobiliary and Pancreatic Surgeon

E-mail: jastephenson{at}doctors.org.uk


   Abstract

The pancreas is a retroperitoneal organ with both endocrine and exocrine functions. It was first described by a Greek physician Herophilus between 335 and 280 BC and was given its name by Ruphos only a few hundred years later. In 1642, Wirsung discovered the pancreatic duct and within three decades Graff investigated its secretory properties. Paul Langerhans described ‘islets of Langerhans’ in 1869 and the first description of pancreatitis as a disease was by Fitz in 1889. Halstead performed the first operation on the pancreas in 1898.


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