AKT answer relating to Back Pain
Answer C. Thoracic pain (especially with nocturnal pain) is a red flag for serious disease. While lytic lesions would be characteristic for myeloma on a skeletal survey, lack of bone density can be a feature. While bone chemistry is important in a patient with myeloma, it would be unusual for example Hypercalcamia to present as bone pain in isolation. Equally, prostatic bone metastases are characteristically sclerotic. Around 20% of cases of myeloma will have non-diagnostic immunoglobulins but positive urine free light chains (Bence-Jones protein).
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